Biochemistry

Situation: One of the largest companies in the Life Science and Biotechnology market came to Pango to develop a product that can consistently homogenize any type of biomedical sample, while separating DNA, RNA and protein in 40 seconds. This was intended to be the fastest solution in the market, utilizing a unique patented motion that delivers consistency and speed.

Solution: Pango exceeded the client's expectations for speed to market, successfully developing the solution in 12 months, rather than planned 16. In addition to meeting functional and performance requirements set by the customer, the product is able to complete a record 48 simultaneous sample extractions. This is a significant achievement and unique feature that clearly differentiates the solution from all competitors—and has opened doors to additional market segments.

Results: The final product has enabled our client to gain significant market share in the Bio-Sample Preparation market and is now one of their most successful products. In addition to the expected sales success, the large number of simultaneous sample extractions has given our client the opportunity to move into additional market segments that have doubled their product revenues. The product is renowned in the industry for its unprecedented quality and a high level of robustness that is required for real-life laboratory conditions.

Physiotherapy

Situation: One of the top three companies in Physiotherapy market came to Pango to develop their first clinical model for Ultrasound and Electro-Therapy, within an aggressive 12-month timeframe. Expectations were running extremely high and technological challenges were significant. As an innovative, practical and affordable solution, this was to be their top-of-the-line product that would set their established brand even further apart from competition.

Solution: The final product was completed within the highly compressed timeframe. The robustness of the product design has allowed the company to expand a single product into an entire family of products, covering a range of market needs not planned for at the beginning of the project. This technological breakthrough has given our client significant cost savings, allowing them to offer customers final end-products at prices that could not be matched by competitors who are offering the same or similar features.

Results: Originally planned as a single product, the final solution turned into an entire family of products at a cost that allowed them to enter into virtually all market segments of Clinical Physical Therapy. Presently, the revenues of this product line account for more than 20% of our client's total revenues. Since that time, we have expanded our partnership with this client. We are now their single partner for medical device design and we manufacture their entire line of the physiotherapy products.

Diagnostics

Situation: A diagnostics company approached Pango to develop a portable instrument capable of simultaneous analysis of 16 chemistry types on a single blood sample. Prior to coming to Pango, they spent 18 months with another partner that resulted in an unsuccessful product, lacking the necessary technical capability and commercial appeal. They were time-bound to get the product to market within 12 months, in their final attempt to commercialize the solution.

Solution: Within 10 months, Pango created a patented solution that was a technical breakthrough, which allows simultaneous analysis of 20+ chemistry types on a blood sample, through electro-chemistry methods. This robust solution allows in-field upgrades for additional chemistry type analysis without replacing the unit. The extension of this single technology into a product family ensures longevity of the product and maximizes per-unit revenue generation.

Results: Initials units have passed market approval tests and the technology was proven to work consistently and with high accuracy. Currently, first customer pre-orders are being placed. This technology is the first working portable solution in the market that is capable of analysis of 16+ chemistry types. Previous portable solutions were constrained to only few chemistry types of analysis. This is significant market differentiator, protected through patents. Due to its portability, a single unit will be able to reach across multiple market segments (portable and laboratory instrumentation), potentially doubling initially expected revenues.

Rehabilitation

Situation: A customer with a portable rehabilitation product featuring patented CES technology had spent 5 months actively seeking a development and manufacturing partner who could provide a full solution-from design through manufacturing and final supply-chain service. The client had experienced a failure on the project with another partner, due to lack of quality and technological limitations. Within 7 days, the client committed to partner with Pango, based on our agreement on the solution, with a guaranteed price and delivery date.

Solution: The portable rehabilitation product met technically stringent requirements for durability, usability and power consumption under very rough usage conditions. Situations where products were placed and had to pass clinical trials included soldiers in active combat in Iraq. Pango exceeded the customer's expectations of a 6-month timeframe, successfully providing an end-to-end complete solution within a 2-month timeframe.

Results: The client was able to get to market 3 times faster, with 50% of total company revenues being generated by this product. Pango is an on-going partner for the full range of services necessary to place and support the product in the marketplace. The client does not have the in-house resources to provide post-sales service, nor the personnel to take care of regulation documentation. So the "full service" provided by Pango is critical to their on-going success.

Implantable Class III Devices

Situation: A micro-miniature electrical stimulator that can be implanted by injection through a needle, the BION is one of the most advanced implantable neuro-stimulators in the research medicine today. The device was developed by a collaboration among researchers at the Alfred Mann Foundation (AMF), Queen's University in Canada, and Illinois Institute of Technology.

The Alfred Mann Institute of University of Southern California requested that Pango provide design and manufacturing services for the next generation of the "Personal Trainer"—a portable device that transmits power to implanted BIONs and provides controller functions for them. This complex project required that design, manufacturing and diagnostics be finished in a 6-month timeframe.

Solution: Pango partnered with the team of AMI engineering, and finished the design services within the timeframe required by the client. Our team worked in close collaborative partnership with the AMI engineers, tackling complex technical issues and meeting every challenge on the project pathway. Even though requirements were adjusted and added along the way, Pango kept our commitment to the initial time guarantee.

Results: The BION Personal Trainer 4 supports a broad range of new applications for the BION implant, including bi-directional communication for closed loop control of FES and cascading multiple transmission coils. Breakthrough technologies developed on this project were able to successfully accommodate applications aimed for the future, such as interfacing complex musculoskeletal modeling software. The new BION Personal Trainer 4 has helped successfully complete initial clinical trials for the BION. The flexible design has created enormous research opportunities to be added in the future. Currently, many research and clinical projects are now based on its expanded capabilities.

Bio-fuel Analysis

Situation: One of the top 5 leaders in the Bio-fuel Analysis market approached Pango for a technology upgrade of their current Bio-fuel Analysis product line. The further manufacturing of their present product was limited by obsolete components and device technology that did not allow for further upgrades necessary to expansion into the additional market segments. Expectations were high, because the client already had on-going highly successful commercial product sales. An absolutely smooth product transition was necessary, so that they would not lose present market share.

Solution: We were the only medical design and development company that was able to commit to a 6-month delivery timeframe with a fixed and guaranteed end-unit price. We moved the client away from their present manual, single-frequency spectroscopy into full-spectrum range spectroscopy that allowed them to place the product into different use-case scenarios, expanding their market reach. By moving away from an old-obsolete MKB-based design into a more appealing touch-screen based user control, our approach enabled us to simplify usability and reduce user time required to run the testing by almost 40%.

Results: A successful commercial product was delivered on time with a significant technology upgrade that empowered the client to expand into additional biochemistry market segments they were not able to capture earlier.

Pango was also able to deliver a 20% of end-unit price reduction, while providing significant improvements on the appeal and usability aspects of the device. The partnership has expanded into a variety of new product design and manufacturing ventures. After dealing with multiple top vendors in the design and manufacturing industry, the client has embraced Pango as a single solution for design, manufacturing and supply chain needs.

Medical Spa

Situation: A start-up Medical Spa product manufacturing company came to Pango to design, develop and manufacture a new breakthrough product for the medical spa market, based on previously patented technology. The aggressive timeframe was 6 to 8 months for completion of a product that required building it from the scratch, with a limited set of existing initial requirements.

Solution: Pango led the client through a usability analysis, to bridge the gap between initial expectations, overall performance requirements and final unit specifications. The modular touch-screen is integrated into an aesthetically attractive device that has by far exceeded customer requirements and expectations. Pango has fully cleared the certification processes for UL, CE and the FDA on behalf of the client.

Results: The sophisticated aesthetic design of the product has helped the customer launch it in the market with great success. The unit has shown results immediately upon launching. The client was able to secure 5 major dedicated distributors for the product nationwide and is expecting initial sales to reach $4 million. They are currently experiencing great success for their very first launch stage of the product.